
📢We are excited to share our upcoming presentation at MicroTAS 2025 which will take place from November 2–6, 2025, in Adelaide, Australia.
We will present our work on a
“Microfluidic Platform for Multiple Sequential Chemical Stimuli with Bidirectional Flow: Enabling Diffracted X-ray Tracking Method of TRPV1 Dynamics.”
💡This microfluidic device enables the real-time observation of stimulus-specific conformational changes in TRPV1 channels at the single-molecule level using DXT (Diffracted X-ray Tracking). Our approach overcomes conventional single-stimulus limitations by enabling uniform and reversible switching among acidic, neutral, and capsaicin-containing solutions, leading to understand how ion channels transition across diverse chemical environments.
📍 Session Info:
– Day & Time: Wednesday, 5 November (14:55 – 16:55)
– Poster#: A095.W
– Authors: Kaito Shimizu, Yusuke Asagoe, Hirofumi Shimizu, and (Presenter) Yoshikazu Hirai
Looking forward to meeting you in Adelaide and discussing the future of microfluidics and ion channel biophysics!